Prognostic Value of Electrophysiological Markers in Alzheimer's Disease
作者:
Gregory Swanwick,
Michael Rowan,
Robert Coen,
Davis Coakley,
Brian Lawlor,
期刊:
American Journal of Geriatric Psychiatry
(OVID Available online 1999)
卷期:
Volume 7,
issue 4
页码: 335-338
ISSN:1064-7481
年代: 1999
出版商: OVID
关键词: Alzheimer's Disease;Research Techniques;Neurophysiology;Prognostic Evaluation
数据来源: OVID
摘要:
The authors assessed the usefulness of event-related potentials (ERP) and flash visual evoked potentials (FVEP) as prognostic markers in a sample of 25 subjects with probable Alzheimer's disease (AD). ERP and FVEP recordings were obtained from 21 and 23 subjects, respectively. Ranking of the annual rate of change in cognitive scales vs. baseline ERP/FVEP latencies was compared, and those with longer FVEP N2component latencies showed slower subsequent rates of decline (τ=0.32; z=2.16; P=0.015), suggesting that further study of FVEP responses as prognostic markers in AD is warranted.
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