Stimulation de la sécrétion insulinique par les acides gras à chaîne moyenne de l’alimentation chez le lapereau
作者:
Jean Pierre Perret,
Nicole Guiffray,
Pierre Mottaz,
期刊:
Annals of Nutrition and Metabolism
(Karger Available online 1983)
卷期:
Volume 27,
issue 2
页码: 153-161
ISSN:0250-6807
年代: 1983
DOI:10.1159/000176635
出版商: S. Karger AG
关键词: Insulin;Glycogen;Medium-chain fatty acids;Rabbit
数据来源: Karger
摘要:
In the young rabbit, immunoreactive serum insulin (IRI) significantly rises during the first 5 min after suckling and then 20–60 min later, at which time the maximum level is reached. Blood glucose levels remain stable, blood ketone bodies increase 2.7 times and the liver glycogen levels decrease. Replacement of maternal milk by an equal volume of 0.9% NaCl, 2% lactose or 3.5 % glycerol does not induce any change in IRI. IRI significantly rises if solutions of bovine milk proteins or skimmed rabbit’s milk are administered. This effect is quickened and strengthened by the addition of coconut oil or lipids of rabbit’s milk whereas sunflower oil is ineffective. It is suggested that medium-chain fatty acids, major components of rabbit’s milk lipids, play an important role in the regulation of insulin secretion in the young
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