Meta‐Analysis of Randomized Controlled Trials Comparing Laparoscopic and Open Appendectomy
作者:
Jane Garbutt,
Nathaniel Soper,
William Shannon,
Anna Botero,
Benjamin Littenberg,
期刊:
Surgical Laparoscopy and Endoscopy
(OVID Available online 1999)
卷期:
Volume 9,
issue 1
页码: 17-26
ISSN:1051-7200
年代: 1999
出版商: OVID
关键词: Meta-analysis;Laparoscopy;Appendectomy;Controlled trials
数据来源: OVID
摘要:
Summary:We performed a meta-analysis to determine whether laparoscopic or open appendectomy gives better outcomes for patients with suspected acute appendicitis. Studies were selected from the MEDLINE database, personal files, and meeting abstracts. Eleven of 21 randomized controlled trials were included in the meta-analysis. Pooled effect size estimates were calculated using a random effects model. Laparoscopic appendectomy reduced time to full functioning by 5.48 days (95% confidence interval [CI] 3.70 to 7.26; p < 0.001), improved postoperative pain at 24 hours measured by a visual analog scale from 0 to 10 by 1.19 points (95% CI −2.14 to −0.24 points; p = 0.014), and decreased the absolute risk for wound infection by 3.2% (95% CI −5.6% to −0.8%; p = 0.009). Operating time was increased by 17.12 min (95% CI 14.19 to 20.03; p < 0.0001). There was no difference between the two surgeries for length of hospital stay, readmission rate, and intra-abdominal abscess formation. Laparoscopic appendectomy improves patient outcomes.
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