Certain investigations on the effective bond strength of gum adhesive extracted from kendu (Diospyros cordifolia Roxb) fruit have been studied with respect to different interfaces such as general-purpose wood-wood, teakwood-teakwood, plywood-plywood, glass-glass, PMMA-wood, PVC-PVC. LDPE-LDPE, HDPE-HDPE, and PMMA-PMMA. The effects of different parameters such as curing temperature, curing time, thickness of specimens, and presolvent treatments on the bond strength of kendu fruit adhesive (KFA) are investigated. The bond strengths of KFA under different hazardous environments such as boiling water, saline water, and kerosene oil, acidic as well as alkaline solutions for the teakwood-teakwood interface have also been examined. A comparative account of studies of the effective bond strength of KFA with three different commercial synthetic adhesives such as Varnicol, Quickfx, and Araldite is reported. The KFA shows a superior bond strength for general-purpose wood-wood adhesion. Its bond strength is also comparable with synthetic adhesives for certain plastic-plastic as well as teakwood-teakwood adhesions. The retention of effective bond strength of KFA in various hazardous atmosphere remarkably encourages an industrial-grade adhesive formulation through proper R&D investigations. Adequate modifications and informations are required for an improved adhesive formulation from this natural adhesive to meet the industrial standard.