Adenine Nucleotide Concentrations and Energy Charge in Muscle of Chronic Haemodialysis Patients
作者:
Wayne G. Cleminson,
Keith L. Manchester,
Wayne J. Diesel,
Larry P. Margolius,
期刊:
Nephron
(Karger Available online 1992)
卷期:
Volume 60,
issue 2
页码: 232-234
ISSN:1660-8151
年代: 1992
DOI:10.1159/000186745
出版商: S. Karger AG
关键词: Haemodialysis;Adenine nucleotides;Energy charge
数据来源: Karger
摘要:
Adenine nucleotide concentrations and energy charge ratios were measured in muscle samples collected during transplant surgery of 7 patients suffering from chronic renal failure and undergoing haemodialysis. The energy charge ratio of 0.75 in the muscle of transplant patients was significantly lower (p < 0.01) than that of 0.89 found in muscle from controls. The lower energy charge ratio and increased concentrations of adenosine diphosphate and adenosine monophosphate may contribute to the patients’ reduced exercise ability and their poor metabolic stat
点击下载:
PDF
(428KB)
返 回