Amperometric and Conductimetric Methods for Simultaneous Determination of Captopril and Bendroflumethiazide
作者:
MohamedE. Mohamed,
HassanY. Aboul-enein,
期刊:
Analytical Letters
(Taylor Available online 1985)
卷期:
Volume 18,
issue 20
页码: 2591-2603
ISSN:0003-2719
年代: 1985
DOI:10.1080/00032718508064489
出版商: Taylor & Francis Group
关键词: Amperometry;Conductimetry;Pharmaceutical analysis;Simultaneous assay of captropril and bendroflumethiazide.
数据来源: Taylor
摘要:
The mixture of captopril (antihypertensive) and bendroflumethiazide (diuretic) was assayed using conductimetric and amperometric methods. Each method was applied for the analysis of laboratory-made sample mixtures in authentic and dosage forms. For captopril, the amperometric and conductimetric methods gave mean percent recoveries of 100.2 ± 1.2 and 99.6 ± 1.2, respectively. These results have shown good agreement when compared with other methods in the literature. When applied to bendroflumethiazide the conductimetric method gave percent recovery of 98.5 ± 1.6 which agreed closely with the spectrophotometric pharmacopoeial method.
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