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Cyanohydrin Alkylation Approach to A Chiral A-Ring Synthon For 1α,25-Dihydroxyvitamin D3

 

作者: Takashi Takahashi,   Takayuki Doi,   Makoto Nakazawa,   Haruo Yamada,  

 

期刊: Natural Product Letters  （Taylor Available online 1993）
卷期: Volume 1, issue 4  

页码: 299-304

 

ISSN:1057-5634

 

年代: 1993

 

DOI:10.1080/10575639308050064

 

出版商: Taylor & Francis Group

 

关键词: 1α,25-dihydroxyvitamin D3;A-ring synthon;cyanohydrin alkylation;d-mannitol

 

数据来源: Taylor

 

摘要:

We report here the synthesis of a chiral A-ring synthon for 1α, 25-dihydroxyvitamin D3starting fromd-mannitol by using the cyanohydrin cyclization methodology.

 

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