Peritoneal Carcinomatosis in Germ-Cell TumorRelations With Retroperitoneal Lymph Node Dissection
作者:
F. Andre,
K. Fizazi,
S. Culine,
J. Droz,
M. Gatineau,
Y. Takahashi,
S. Oudard,
C. Theodore,
期刊:
American Journal of Clinical Oncology: Cancer Clinical Trials
(OVID Available online 2000)
卷期:
Volume 23,
issue 5
页码: 460-462
ISSN:0277-3732
年代: 2000
出版商: OVID
关键词: Germ cell tumors;Peritoneal carcinomatosis;Retroperitoneal lymph node dissection;Chemotherapy;Testicular neoplasms.
数据来源: OVID
摘要:
Peritoneal carcinomatosis from germ-cell tumor has rarely been described, and thus remains largely unknown. We report here five cases involving this entity. All five patients had embryonal carcinoma in their primary germ-cell tumor. Four of them had undergone retroperitoneal lymph node dissection (RPLND), and viable malignant cells were found. RPLND was performed for relapses (n = 3) and as primary therapy for stage II disease (n = 1). The peritoneum was the only site of relapse in three patients, and was associated with pleural effusion in one. The time to relapse after RPLND ranged from 6 to 14 months. One patient sustained injury to lymph nodes during RPLND, and another patient had a peritoneal xanthelasma. The only three patients already described in the literature underwent RPLND or surgical biopsy. All these observations suggest a striking relation between RPLND and occurrence of subsequent peritoneal carcinomatosis.
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