The Importance of Confounding Factors in the Evaluation of Neuropsychological Changes in Patients Infected with Human Immunodeficiency Virus
作者:
Jean Wilkins,
Kevin Robertson,
Charles van der Horst,
Wendy Robertson,
John Fryer,
Colin Hall,
期刊:
Journal of Acquired Immune Deficiency Syndromes
(OVID Available online 1990)
卷期:
Volume 3,
issue 10
页码: 938-942
ISSN:0894-9255
年代: 1990
出版商: OVID
关键词: HIV infection;Neuropsychological effects;Confounding factors.
数据来源: OVID
摘要:
SummaryThere are conflicting reports on the early effects of human immunodeficiency virus (HIV) infection on the nervous system. Some studies have suggested that there may be early cognitive impairment, while others have refuted this. We describe the results of extensive neuropsychological testing in a group of 40 infected subjects. These indicate that the degree of impairment is closely related to confounding factors other than the infection itself. Our conclusion is that the early stages of HIV disease are not associated with a high frequency of cognitive impairment if these confounding variables are taken into consideration.
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