首页   按字顺浏览 期刊浏览 卷期浏览 Lack of RH C/E expression in the Rhesus D– phenotype is the result of a gene deletion
Lack of RH C/E expression in the Rhesus D– phenotype is the result of a gene deletion

 

作者: T. BLUNT,   F. STEERS,   G. DANIELS,   B. CARRITT,  

 

期刊: Annals of Human Genetics  (WILEY Available online 1994)
卷期: Volume 58, issue 1  

页码: 19-24

 

ISSN:0003-4800

 

年代: 1994

 

DOI:10.1111/j.1469-1809.1994.tb00722.x

 

出版商: Blackwell Publishing Ltd

 

数据来源: WILEY

 

摘要:

SUMMARYWe have investigated the arrangement of genes in the rare Rh (Rhesus) partial null condition D–, Southern blot and PCR studies under conditions which distinguish the highly homologous RH D and RH C/E genes show that in an Icelandic family with the D– haplotype at least 85% of the RH C/E gene is deleted. This finding is in contrast to one other published case of this phenotype, where intact RH D and C/E genes were found, and also to the full amorph Rhnullphenotype, where an intact RH C/E gene was found, accompanied by the deletion of the RH D gene typical of Rh D‐negative indivi

 

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