Toxicological effects of ziram, thiram, and dithane M‐45 assessed by sperm shape abnormalities in mice
作者:
E. Hemavathi,
M. A. Rahiman,
期刊:
Journal of Toxicology and Environmental Health
(Taylor Available online 1993)
卷期:
Volume 38,
issue 4
页码: 393-398
ISSN:0098-4108
年代: 1993
DOI:10.1080/15287399309531727
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
The three commonly used dithiocarbamate fungicides ziram, thiram, and dithane M‐45 were investigated for their mutagenic and carcinogenic potency using sperm shape abnormalities in mice. The fungicides were administered intraperitoneally in single and cumulative doses. All three of the fungicides tested were found to induce significant increase in the frequency of abnormal sperm at all the doses, and a linear dose effect was observed.
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