Sodium lauryl sulfate and recurrent aphthous ulcers: A preliminary study
作者:
HerlofsonBente Brokstad,
BarkvollPål,
期刊:
Acta Odontologica Scandinavica
(Taylor Available online 1994)
卷期:
Volume 52,
issue 5
页码: 257-259
ISSN:0001-6357
年代: 1994
DOI:10.3109/00016359409029036
出版商: Taylor&Francis
关键词: Dentifrice;oral mucosa;recurrent aphthous ulcers
数据来源: Taylor
摘要:
Herlofson BB, Barkvoll P. Sodium lauryl sulfate and recurrent aphthous ulcers. A preliminary study. Acta Odontol Scand 1994;52:257-259. Oslo. ISSN 00016357.Sodium lauryl sulfate (SLS), a synthetic detergent commonly used in dentifrices, is an effective denaturant. The aim of the present study was to investigate the effect of SLS in patients with recurrent aphthous ulcers (RAU). Ten patients with multiple minor RAU participated in the study. The mean incidence of MU was 17.8 during a 3-month period before the study. The patients used a dentifrice containing 1.2% SLS for a test period of 3 months followed by a dentifrice without SLS for the same time period. The results showed a statistically significant decrease in the number of aphthous ulcers from 14.3 after using the SLS-containing dentifrice to 5.1 ulcers after brushing with the SLS-free dentifrice (p<0.05). It is suggested that the denaturing effect of SLS on the oral mucin layer, with exposure of the underlying epithelium, induces an increased incidence of RAU.
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