Experimental Use of Fluoroalkyl Cyanoacrylate in Canine Urethral Anastomosis
作者:
DENNIS A. JACKSON,
TIMOTHY H. BRASMER,
JERRY B. STEVENS,
期刊:
Veterinary Surgery
(WILEY Available online 1980)
卷期:
Volume 9,
issue 1
页码: 13-19
ISSN:0161-3499
年代: 1980
DOI:10.1111/j.1532-950X.1980.tb01645.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
The results of a study designed to evaluate a fluoroalkyl cyanoacrylate tissue adhesive as an adjunct to suture anastomosis of the severed canine pelvic urethra are presented. The urethral anastomotic sites were evaluated by contrast radiography, gross pathology, and histopathology. Urethral anastomosis resulted in a clinically functional urethra in all 6 control dogs (suture anastomosis) and 5 of the 6 test dogs (suture anastomosis plus adhesive). A severe stricture at the anastomotic site developed in 1 dog in the test group. Evidence of leakage was detected by contrast radiography in 1 dog of each group. Microscopic evidence of incomplete closure was detected in 4 control dogs and 2 test dogs. An extensive granulomatous inflammatory reaction was associated with use of the adhesive. The lower incidence of microscopic leakage observed in the test dogs was attributed to fibroplasia induced by the cyanoacrylate and not to the adhesive properties of the cyanoacrylate.
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