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Association between Haptoglobin Groups and Hereditary Predisposition for Bronchial Asthma

 

作者: Nils Fröhlander,   Nils Stjernberg,  

 

期刊: Human Heredity  (Karger Available online 1989)
卷期: Volume 39, issue 1  

页码: 7-11

 

ISSN:0001-5652

 

年代: 1989

 

DOI:10.1159/000153824

 

出版商: S. Karger AG

 

关键词: Haptoglobin;Bronchial asthma;Family history;Adult onset;Atopy

 

数据来源: Karger

 

摘要:

Haptoglobin (Hp) groups were investigated in 148 patients with bronchial asthma. A significant (p < 0.005) deviation from the expected Hardy-Weinberg equilibrium, with a decreased frequency of heterozygotes, was observed among patients with a family history of asthma. This deviation was more pronounced among patients with adult onset of asthma. The presence or absence of atopy had no significant influence on the phenotype distribution.

 

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