Association between Haptoglobin Groups and Hereditary Predisposition for Bronchial Asthma
作者:
Nils Fröhlander,
Nils Stjernberg,
期刊:
Human Heredity
(Karger Available online 1989)
卷期:
Volume 39,
issue 1
页码: 7-11
ISSN:0001-5652
年代: 1989
DOI:10.1159/000153824
出版商: S. Karger AG
关键词: Haptoglobin;Bronchial asthma;Family history;Adult onset;Atopy
数据来源: Karger
摘要:
Haptoglobin (Hp) groups were investigated in 148 patients with bronchial asthma. A significant (p < 0.005) deviation from the expected Hardy-Weinberg equilibrium, with a decreased frequency of heterozygotes, was observed among patients with a family history of asthma. This deviation was more pronounced among patients with adult onset of asthma. The presence or absence of atopy had no significant influence on the phenotype distribution.
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