New processes for the synthesis of 2,6‐dichloro‐3‐methylaniline‐Ph‐UL‐14C and methyl 6‐chloroanthranilate‐Ph‐UL‐14C
作者:
L. H. McKendry,
M. A. Stanga,
期刊:
Journal of Labelled Compounds and Radiopharmaceuticals
(WILEY Available online 1994)
卷期:
Volume 34,
issue 12
页码: 1157-1164
ISSN:0362-4803
年代: 1994
DOI:10.1002/jlcr.2580341205
出版商: John Wiley&Sons, Ltd.
关键词: Carbon‐14;2,6‐dichloro‐3‐methylaniline;methyl 6‐chloroanthranilate;chlorination
数据来源: WILEY
摘要:
AbstractTwo new processes were developed for the synthesis of 2,6‐dichloro‐3‐methylaniline‐Ph‐UL‐14C (1), a key intermediate in the synthesis of a Dow Elanco experimental product presently being considered for commercialization. Both processes afford product in much higher yields than that previously reported in the literature. One of the processes was subsequently applied to the synthesis of methyl 6‐chloroanthranilate‐Ph‐UL‐14C (12), used as an intermediate for a secon
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