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New processes for the synthesis of 2,6‐dichloro‐3‐methylaniline‐Ph‐UL‐14C and methyl 6‐chloroanthranilate‐Ph‐UL‐14C

 

作者: L. H. McKendry,   M. A. Stanga,  

 

期刊: Journal of Labelled Compounds and Radiopharmaceuticals  (WILEY Available online 1994)
卷期: Volume 34, issue 12  

页码: 1157-1164

 

ISSN:0362-4803

 

年代: 1994

 

DOI:10.1002/jlcr.2580341205

 

出版商: John Wiley&Sons, Ltd.

 

关键词: Carbon‐14;2,6‐dichloro‐3‐methylaniline;methyl 6‐chloroanthranilate;chlorination

 

数据来源: WILEY

 

摘要:

AbstractTwo new processes were developed for the synthesis of 2,6‐dichloro‐3‐methylaniline‐Ph‐UL‐14C (1), a key intermediate in the synthesis of a Dow Elanco experimental product presently being considered for commercialization. Both processes afford product in much higher yields than that previously reported in the literature. One of the processes was subsequently applied to the synthesis of methyl 6‐chloroanthranilate‐Ph‐UL‐14C (12), used as an intermediate for a secon

 

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