Oncogenes as Novel Targets for Cancer Therapy (Part IV)Regulators of the Cell Cycle and Apoptosis
作者:
Zhuo Zhang,
Mao Li,
Elizabeth R Rayburn,
Donald L Hill,
Ruiwen Zhang,
Hui Wang,
期刊:
American Journal of PharmacoGenomics
(ADIS Available online 2005)
卷期:
Volume 5,
issue 6
页码: 397-407
ISSN:1175-2203
年代: 2005
出版商: ADIS
关键词: Cancer, general;Genomics
数据来源: ADIS
摘要:
This is the final part of a four-part serial review on oncogenes and their potential use as targets for cancer therapy. Previous sections discussed various categories of oncogenes (growth factors, tyrosine kinases, intermediate signaling molecules, and transcription factors) and the advances made in various strategies being used to alter their actions. This part describes four oncogenes, MDM2, BCL2, XIAP, and Survivin, that are involved in regulation of the cell cycle and apoptosis.
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