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Shrinkage Estimators of Relative Potency

 

作者: P.T. Kim,   E.M. Carter,   J.J. Hubert,   K.J. Hand,  

 

期刊: Journal of the American Statistical Association  (Taylor Available online 1993)
卷期: Volume 88, issue 422  

页码: 615-621

 

ISSN:0162-1459

 

年代: 1993

 

DOI:10.1080/01621459.1993.10476314

 

出版商: Taylor & Francis Group

 

关键词: Asymptotic distribution;Bayesian;Frequentist;Parallel line bioassay;Relative potency;Shrinkage estimator

 

数据来源: Taylor

 

摘要:

This article examines the finite and infinite sample properties of the shrinkage estimator, motivated by a Bayesian argument, for the log relative potency, proposed in an earlier paper by Kim, Carter, and Hubert. This estimator can be written in closed form and is shown to have finite mean and finite variance in finite samples. As a consequence, this shrinkage estimator has finite frequentist risk, which is an improvement over the usual maximum likelihood estimator, for all finite sample sizes. Furthermore, it is shown that this estimator asymptotically behaves the same as the usual maximum likelihood estimator.

 

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