Corneal Sensation After Topical Anesthesia
作者:
Keiko,
Nomura Diane,
Singer James,
期刊:
Cornea
(OVID Available online 2001)
卷期:
Volume 20,
issue 2
页码: 191-193
ISSN:0277-3740
年代: 2001
出版商: OVID
关键词: Topical anesthesia;Anesthesiometer;Corneal sensitivity;Lidocaine;Bupivacaine;Tetracaine
数据来源: OVID
摘要:
Purpose.To compare the topical effects of tetracaine, lidocaine, and bupivacaine on corneal sensitivity in normal eyes.Methods.Corneal touch sensitivity was measured with a Cochet-Bonnet anesthesiometer before and at 2.5-minute intervals after instillation of the anesthetic agent, until baseline levels had been reestablished. Seventeen healthy volunteers were randomized into five groups. Group 1 included 0.5% tetracaine (n= 6); group 2, 4% lidocaine (n= 8); group 3, 0.75% bupivacaine (n= 8); group 4, 0.5% tetracaine + 4% lidocaine (n= 5); and group 5, 0.5% tetracaine + 0.75% bupivacaine (n= 7).Results.The duration of anesthesia showed no differences between groups 1, 3, and 5. Although there was no difference between groups 2 and 4, both groups demonstrated significantly longer effects than groups 1, 3, and 5 (p< 0.005).Conclusion.The application of 4% lidocaine results in a significantly prolonged topical anesthetic effect when compared with tetracaine and bupivacaine.
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