In vitroSensitivity of Hospital Strains ofSerratia marcescensto Chemotherapeutic Agents
作者:
L. Verbist,
J. Spaepen,
J. Vandepitte,
期刊:
Chemotherapy
(Karger Available online 1976)
卷期:
Volume 22,
issue 1
页码: 43-54
ISSN:0009-3157
年代: 1976
DOI:10.1159/000221909
出版商: S. Karger AG
关键词: Serratia marcescens;Amikacin;Aminoglycosides;Hospital infections;Multiple antibiotic resistance
数据来源: Karger
摘要:
The susceptibility of 83 non-pigmented Serratia marcescens strains was determined by an agar dilution technique. They originated from miscellaneous pathological specimens submitted to the diagnostic laboratory during a nosocomial infection outbreak in 1974. All strains were completely resistant to 128 μg/ml of cephalothin, colistin sulphomethate, lincomycin and penicillin G. They were also resistant to clinically attainable concentrations of ampicillin, chloramphenicol, erythromycin, novobiocin and tetracycline. With regard to drugs with some activity, 84% of the strains were susceptible to nalidixic acid, 48% to sulphamethoxazole, 57% to streptomycin, 60% to kanamycin, 61% to gentamicin, 85% to co-trimoxazole and 100% to amikacin. Environmental strains isolated from the infected units were strikingly more sensitive than the patient strains
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