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Gentamicin, norfloxacin and lysozyme concentration in human tears: in vivo and in vitro study

 

作者: A. M. Bron,   C. Bonnin,   C. Garcher,   A. Lallemand,  

 

期刊: Acta Ophthalmologica  （WILEY Available online 1992）
卷期: Volume 70, issue 6  

页码: 750-753

 

ISSN:1755-375X

 

年代: 1992

 

DOI:10.1111/j.1755-3768.1992.tb04881.x

 

出版商: Blackwell Publishing Ltd

 

关键词: ocular surface;infection;gentamicin;lysozyme

 

数据来源: WILEY

 

摘要:

AbstractHen's egg lysozyme (HEL) activity was measured in vitro with gentamicin and norfloxacin by a turbidimetric technique. Gentamicin at the concentration of 10‐3M inhibited HEL activity by 39%, while 10‐3M norfloxacin did not affect HEL activity. However, an in vivo study in healthy persons did not show any significant statistical difference in tear lysozyme activity when 0.3% gentamicin or 0.3% norfloxacin were topically appl

 

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