Frequency and Significance of the Major and Minor Features of Hanifin and Rajka among Patients with Atopic Dermatitis
作者:
E. Rudzki,
Z. Samochocki,
P. Rebandel,
E. Saciuk,
W. Gałecki,
A. Rą;czka,
A. Szmurło,
期刊:
Dermatology
(Karger Available online 1994)
卷期:
Volume 189,
issue 1
页码: 41-46
ISSN:1018-8665
年代: 1994
DOI:10.1159/000246781
出版商: S. Karger AG
关键词: Asthma;Atopic dermatitis features;Cataract;Dennie-Morgan infraorbital fold;IgE;Food intolerance;Xerosis;Itch
数据来源: Karger
摘要:
In 481 patients with atopic dermatitis (AD), 4 major features of Hanifin and Rajka were found in 72%, and in 96% over 6 minor features were seen, which is much more than the minimum required by these authors for making a ‘firm diagnosis’. The incidence of particular minor features in all patients was varying significantly, and in subgroups of patients they appeared with different frequency. For example, asthma occurred more often in AD patients with the onset of skin lesions before the 6th month of life, and food intolerance was more frequently observed in patients with very high serum IgE level. In the control groups some minor features also occur but less frequently than in AD patients. We conclude that the anterior neck folds and Dennie-Morgan infraorbital fold should be regarded as minor AD featu
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