Controlled Release from Crosslinked Poloxamer Hydrogels
作者:
T. K. Law,
T. L. Whateley,
A. T. Florence,
期刊:
British Polymer Journal
(WILEY Available online 1986)
卷期:
Volume 18,
issue 1
页码: 34-36
ISSN:0007-1641
年代: 1986
DOI:10.1002/pi.4980180109
出版商: John Wiley&Sons, Ltd
关键词: hydrogel;poloxamer;Pluronic;controlled release
数据来源: WILEY
摘要:
AbstractChemically modified derivatives of the copolymeric poloxamer surfactants have been polymerised to form crosslinked, swelling hydrogels. Mixtures of derivatives of poloxamers 188 and 181 form gels which show increased swelling with increased content of the more hydrophilic poloxamer 188. The rate of release of benzoic andp‐hydroxybenzoic acids also increases with increasing content of poloxamer 188. Release rate data have been analysed in terms of the swelling controlled release model for these hydrogel
点击下载:
PDF
(246KB)
返 回