Teratogenic effects of noise and cadmium in mice: Does noise have teratogenic potential?
作者:
Mariko Murata,
Hiroshi Takigawa,
Hiroshi Sakamoto,
期刊:
Journal of Toxicology and Environmental Health
(Taylor Available online 1993)
卷期:
Volume 39,
issue 2
页码: 237-245
ISSN:0098-4108
年代: 1993
DOI:10.1080/15287399309531748
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
The teratogenicity of combined exposure to noise and cadmium was studied in mice. ICR mice were exposed to a wide octave‐band of noise at 100 dB(C) for 6 h on d 7 of pregnancy in one of two ways: continuous exposure or intermittent (15 min on/15 min off). Cadmium sulfate at 1 or 2 mg/kg was intraperitoneally injected on d 7 of pregnancy. Four groups were exposed to both cadmium and noise. On d 18 of pregnancy, fetuses were examined for external and skeletal malformations. Another experiment was performed with two other patterns of noise exposure: continuous exposure for 3 h, and intermittent exposure (5 min on/5 min off) for 6 h on d 7 of pregnancy.
点击下载:
PDF (487KB)
返 回