Visual Loss With Langerhans Cell HistiocytosisMultifocal Central Nervous System Involvement
作者:
Oliver Job,
Norman Schatz,
Joel Glaser,
期刊:
Journal of Neuro-Ophthalmology
(OVID Available online 1999)
卷期:
Volume 19,
issue 1
页码: 40-53
ISSN:1070-8022
年代: 1999
出版商: OVID
关键词: Langerhans cell histiocytosis;Visual pathway involvement;Optic chiasm;Optic nerve;Infiltrative optic neuropathy;Radiation therapy;Magnetic resonance imaging
数据来源: OVID
摘要:
A 42-year-old woman with a 6-year history of diabetes insipidus and progressive hypersomnolence presented with visual loss. Neuroimaging showed infiltration in the hypothalamus, the optic nerve, and the chiasm, as well as multiple lesions in other areas of the brain parenchyma. Biopsy showed Langerhans cell histiocytosis. This is an unusual presentation of Langerhans cell histiocytosis, involving the visual pathways without manifestations outside of the central nervous system. The differential diagnosis and the magnetic resonance imaging findings will be discussed.
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