The Antenatal Blood Gas and Acid-Base Status of Normal Fetuses and Hydropic Fetuses With Bart Hemoglobinopathy
作者:
FON-JOU HSIEH,
FONG-MING CHANG,
TSANG-MING KO,
PAO-LIN KUO,
DAW-YUAN CHANG,
HSI-YAO CHEN,
期刊:
Obstetrics & Gynecology
(OVID Available online 1989)
卷期:
Volume 74,
issue 5
页码: 722-725
ISSN:0029-7844
年代: 1989
出版商: OVID
数据来源: OVID
摘要:
Funipuncture offers direct access to the fetal circulation. The blood gas and acid-base status of the fetus can be studied, and fetal hypoxia and acidosis can be diagnosed directly. To establish normal ranges of fetal blood gas and acid-base status, we analyzed umbilical venous blood samples obtained by funipuncture from 62 normal fetuses (20–35 weeks). These fetuses were studied because of suspected fetal diseases and were subsequently proved to be normal by the fetal blood examinations. Umbilical vein pH and pO2decreased whereas pCO2and bicarbonate increased with gestational age. The umbilical vein base excess did not correlate with gestational duration, but oxygen saturation tended to decrease with gestational age. Twenty hydropic fetuses with Bart hemoglobinopathy were also studied; they were found to be more acidotic, hypoxic, and hypercarbic than normal fetuses
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