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Isolation of Multiple Cytomegalovirus Strains from a Patient with Adult T Cell Leukemia

 

作者: Yoshito Eizuru,   Yoichi Minamishima,   Miwako Hirose,   Katsumi Ogata,   Akihiko Tajiri,   Shigeru Tada,   Shohei Inoue,   Kazutoshi Kaketani,   Akinobu Sumiyoshi,  

 

期刊: Intervirology  （Karger Available online 1990）
卷期: Volume 31, issue 6  

页码: 355-358

 

ISSN:0300-5526

 

年代: 1990

 

DOI:10.1159/000150172

 

出版商: S. Karger AG

 

关键词: Dual infection;Cytomegalovirus;Adult T cell leukemia

 

数据来源: Karger

 

摘要:

A 66-year-old male with adult T cell leukemia had an ulcer on the left medial thigh. The biopsy of the skin lesion revealed enlarged endothelial cells with acidophilic intranuclear inclusion bodies, suggesting cytomegalovirus (CMV) infection. At autopsy, CMV was isolated from a nodular skin lesion of the scrotum. The urine constantly tested positive for CMV. Restriction endonuclease cleavage analysis of DN A of the isolates from the skin and urine indicated that this patient was infected with two different strains of CMV.

 

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