The macroscopic and histological appearance of cutaneous incisions closed with polyglecaprone 25 (Monocryl)* and polyglactin 910 (Vicryl)†suture materials were compared in four dogs. Polyglecaprone 25 compared favourably to polyglactin 910 suture material for closure of canine skin incisions, and was associated with significantly less tissue reaction in the early phases of the healing process than was polyglactin 910 suture material. This difference was not present at later evaluation times.