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A Comparative Study of the Haemostatic Properties and Cardiovascular Effects of Adrenaline and Ornipressin in Children during Enflurane Anaesthesia

 

作者: A. J. Sharkey,   M. D. Brennen,   Maureen P. O'Neill,   G. W. Black,  

 

期刊: Acta Anaesthesiologica Scandinavica  (WILEY Available online 1982)
卷期: Volume 26, issue 4  

页码: 368-370

 

ISSN:0001-5172

 

年代: 1982

 

DOI:10.1111/j.1399-6576.1982.tb01784.x

 

出版商: Blackwell Publishing Ltd

 

数据来源: WILEY

 

摘要:

In a randomised, double‐blind trial, haemostatic and cardiovascular effects of ornipressin and adrenaline were compared in 30 children requiring surgery for “bat‐ear” deformity. Mean total blood loss was 14.3 ml with ornipressin and 11.7 ml with adrenaline, this difference being insignificant. There was a significant and progressive reduction in mean heart rate in children who received ornipressin. from 134 to 116 bpm (P<0.0.5). and a significant rise from 127 to 134 bpm (P<0.05) with adrenaline. Mean systolic pressure was unaltered by ornipressin but was significantly increased from 97 to 105 mmHg (P<0.05) in children receiving adrenaline. Ornipressin is as effective a haemostatic agent as adrenaline and the rises in heart rate and systolic pressure associated with adrenaline, which are factors known to predispose to the onset of ventricular dysrhythmias, do not occur with orni

 

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