Variations in Cytotoxicity During Ozonation of Substituted Aromatics
作者:
L.H. Pottenger,
E. Gilbert,
J.C. Block,
P. Hartemann,
期刊:
Ozone: Science & Engineering
(Taylor Available online 1980)
卷期:
Volume 2,
issue 1
页码: 25-37
ISSN:0191-9512
年代: 1980
DOI:10.1080/01919518008550866
出版商: Taylor & Francis Group
关键词: Ozonation;substituted aromatics;oxidation products;biodegradability;cytotoxicity
数据来源: Taylor
摘要:
The cytotoxicity test, using BGM cells and a colorimetric protein assay (Lowry, 1951) was a more sensitive modification of those described by Christian (1973) and Elias, et al. (1978). The cytotoxicity varied during ozonation, reaching a maximum after 50%90% degradation of the initial compound; aniline solution, 6.5x103M, showed a maximum cytotoxicity at 90% degradation after 60 min of ozonation, which decreased to 0% after 180 min 03. Ozonated nitro– and chloro–cresol solutions showed similar patterns. The variations in cytotoxicity seem to be related to the formation of intermediate oxidation products. The preliminary results suggest that this type of test, being both simple and fast, would be useful in toxicological screening of wastewater.
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