Fatal fluoride toxicity from silver brazing flux ingestion
作者:
JAMES TILLEARD,
期刊:
Emergency Medicine
(WILEY Available online 1994)
卷期:
Volume 6,
issue 1
页码: 12-16
ISSN:1035-6851
年代: 1994
DOI:10.1111/j.1442-2026.1994.tb00431.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
ABSTRACTAim:To describe a case of fluoride poisoning due to ingestion of silver brazing flux and review the pathophysiology and treatment of such ingestions.Introduction:The dominant hazardous constituent of silver brazing flux is KHF2(potassium hydrogen fluoride). This compound is toxic, corrosive and rapidly absorbed from the gastrointestinal tract to produce systemic fluoride toxicity.Case report:A woman ingested an unknown amount of silver brazing flux and was brought to the Emergency Department hypotensive and obtunded. Despite vigorous resuscitation and electrolyte replacement she developed refractory ventricular fibrillation and died eight hours later in intensive care.Discussion:Hydrogen fluoride and its salts are widely used in industrial and domestic products but poisoning by these agents is uncommon. Rapid absorption produces systemic fluoride toxicity. This generates hypocalcaemia, hypomagnesaemia and hyperkalaemia with death resulting from refractory ventricular arrhythmias. These chemicals are corrosive and may cause haemorrhage or perforation of the gastrointestinal tract.Conclusion:Survival from such ingestions is rare. Early recognition and appropriate treatment are essential to optimise outcome.
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