Spectrophotometrio and Titrimetric Determination of Certain Adrenergic Drugs
作者:
W.I. Mohamed,
F.B. Salem,
期刊:
Analytical Letters
(Taylor Available online 1984)
卷期:
Volume 17,
issue 3
页码: 191-203
ISSN:0003-2719
年代: 1984
DOI:10.1080/00032718408065278
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Potassium bromate was applied to the determination of adrenaline, noradrenalhe, isopropylnoradrenaline and methyl-dopa. Direct potentiometric and visual indicator titration methods as well as back-titration procedures have been developed for their determination. Oxidation of these catechol-amines produce aminochmme derivatives at pH 11.0 which could be measured spectrophotometrically at 465 nm. Beer's law is obeyed in the concentration range from 0.04 to 1.4 mg adrenaline, 0.04 to 1.27 ag noradrenaline, 0.06 to 1.4 mg isopropylnoradrenaline and from 0.04 to 0.65 methyldopa.
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