Ultra‐high‐strength absorbable self‐reinforced polyglycolide (SR‐PGA) composite rods for internal fixation of bone fractures:In vitroandin vivostudy
作者:
P. Törmälä,
J. Vasenius,
S. Vainionpää,
J. Laiho,
T. Pohjonen,
P. Rokkanen,
期刊:
Journal of Biomedical Materials Research
(WILEY Available online 1991)
卷期:
Volume 25,
issue 1
页码: 1-22
ISSN:0021-9304
年代: 1991
DOI:10.1002/jbm.820250102
出版商: John Wiley&Sons, Inc.
数据来源: WILEY
摘要:
AbstractThe ultra‐high‐strength, self‐reinforced (SR) absorbable polymeric composites, consisting of reinforcement elements, like fibers, and of matrix polymer which have the same chemical element composition as reinforcement, were defined. A method to manufacture self‐reinforced, absorbable polyglycolide (SR‐PGA) rods of polyglycolide sutures (Dexon) by sintering them partially together at elevated temperature and pressure was presented. The rods with nominal diameters of 1.5 mm, 2.0 mm, 3.2 mm, and 4.5 mm showed initial bending modulus and strength values of 8–15 GPa and 220–405 MPa, respectively. Their initial shear strengths were 165–255 MPa. The smallest rods (diam. 1.5 mm) lost their mechanical strength after implantation in the subcutis of rabbits in 4–5 weeks while the thickest rods retained their strength over 8 weeks. The ultra‐high‐strength SR‐PGA rods were concluded to be suitable for fixation of cancellous bone fractures, osteotomies, and epiphyseal plate fractures where the fixation is not exposed to excessive mechanical stresses and where the loads are predomin
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