Evaluation of Cyanide Exposure and Its Effect on Thyroid Function of Workers in a Cable Industry
作者:
Kishore Banerjee,
Anupam Bishayee,
P. Marimuthu,
期刊:
Journal of Occupational and Environmental Medicine
(OVID Available online 1997)
卷期:
Volume 39,
issue 3
页码: 258-260
ISSN:1076-2752
年代: 1997
出版商: OVID
数据来源: OVID
摘要:
A thyroid-hormone evaluation of workers dealing with cyanide compounds in an electroplating process of a cable industry was carried out. Serum thiocyanate (SCN) levels of 35 nonsmoking copper-ply employees were assayed by a ferric-chloride color test. The mean SCN concentration of these employees was 316 ± 15 µmol/L, which was significantly (P < 0.01) higher than that of control subjects (90.8 ± 9.02 µmol/L). Serum thyroxine (T4), triiodothyronine (T3), and thyroid-stimulating hormone (TSH) concentrations of exposed workers were compared with those of 35 control subjects. Cyanide exposure resulted in a decrease in T4and T3concentrations (P < 0.05) and an increase in TSH concentration (P < 0.05), compared with the control subjects. The serum T4level was found to be negatively correlated (r = -0.363, P < 0.05), whereas the TSH level was positively correlated (r = 0.354, P < 0.05), with SCN concentration in the exposed group. The study suggests that occupational cyanide exposure in the industry impairs thyroid function.
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