Hydergine in Senile Mental Impairment
作者:
Dieter M. Loew,
Claude Weil,
期刊:
Gerontology
(Karger Available online 1982)
卷期:
Volume 28,
issue 1
页码: 54-74
ISSN:0304-324X
年代: 1982
DOI:10.1159/000212511
出版商: S. Karger AG
关键词: Senile mental impairment;Assessment;Therapy;Hydergine;SCAG rating scale;Psychometry;EEG;Serum prolactin
数据来源: Karger
摘要:
Among gerontopsychiatric drugs, Hydergine is pharmacologically characterized by agonist action at central dopamine and serotonin receptors. This review presents a summary of the results obtained with Hydergine in numerous controlled trials in patients with senile mental impairment. Assessment was carried out by means of a rating scale (mainly the Sandoz Clinical Assessment Geriatric, or SCAG, scale), psychometric tests (e.g. the Nuremberg Geriatric Inventory, or NGI), and the EEG. Hydergine also lowers serum prolactin, though a correlation with clinical improvement has not been established as yet. In the discussion, the need for objective, measurable and precise indicators in gerontopsychiatry is stressed.
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