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Synthesis of c-5′-nor-Dideoxycarbanucleosides Structurally Related to Neplanocin C

 

作者: MariaJ. Comin,   CarlosA. Pujol,   ElsaB. Damonte,   JuanB. Rodriguez,  

 

期刊: Nucleosides and Nucleotides  （Taylor Available online 1999）
卷期: Volume 18, issue 10  

页码: 2219-2231

 

ISSN:0732-8311

 

年代: 1999

 

DOI:10.1080/07328319908044877

 

出版商: Taylor & Francis Group

 

数据来源: Taylor

 

摘要:

Purine carbanucleosides built on a 6-oxabicyclo[3.1.0]hexane template were synthesized from readily available 2-cyclopentenone employing a Mitsunobu reaction to incorporate the base onto the carbocyclic ring. Both adenosine and guanosine analogues exhibited moderate antiviral activity.

 

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