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A Phase II Trial of Sequential MTx and 5-FU Alternated with 4-Epidoxorubicin and Cisplatin in Advanced Gastric Cancer

 

作者: TaalB. G.,   ten BokkelW. W. Huinink,   SimonettiG.,   FranklinH.,   McVieJ. G.,  

 

期刊: Cancer Investigation  （Taylor Available online 1990）
卷期: Volume 8, issue 5  

页码: 501-504

 

ISSN:0735-7907

 

年代: 1990

 

DOI:10.3109/07357909009012074

 

出版商: Taylor&Francis

 

数据来源: Taylor

 

摘要:

AbstractTwenty-one patients with advanced gastric adenocarcinoma were treated with a combination chemotherapy schedule of sequential methotrexate and 5-fluorouracil alternated with 4-epidoxorubicin and cisplatin. This scheme was active, with 7 partial responses leading to a response rate of 33% (±20%). In two cases the tumor became operable. No severe toxicity developed and the treatment was usually well tolerated.

 

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