Tc-99m MIBI, Tc-99m Tetrofosmin, and Tc-99m (V) DMSA Accumulation in Recurrent Malignant Thymoma
作者:
SEONG JANG KIM,
IN KIM,
YONG KIM,
期刊:
Clinical Nuclear Medicine
(OVID Available online 2002)
卷期:
Volume 27,
issue 1
页码: 30-33
ISSN:0363-9762
年代: 2002
出版商: OVID
关键词: Malignant Thymoma;Tc-99m MIBI;Tc-99m Tetrofosmin;Tc-99m (V) DMSA
数据来源: OVID
摘要:
Thymoma is the most common primary tumor of the anterior mediastinum, accounting for 20% to 30% of all mediastinal tumors. The recurrence rate after total resection of the thymoma ranges from 8% to 18%. The authors describe a patient with recurrent malignant thymoma imaged with Tc-99m MIBI, Tc-99m tetrofosmin, and Tc-99m (V) DMSA. Early and delayed Tc-99m MIBI and Tc-99m tetrofosmin scintigraphy showed increased uptake in the mediastinal area, as did Tc-99m (V) DMSA scintigraphy. Coronal SPECT images obtained with Tc-99m MIBI, Tc-99m tetrofosmin, and Tc-99m (V) DMSA showed increased uptake in the mediastinal lesion seen on a computed tomograph of the chest. However, the normal blood-pool activity of the heart and great vessels imaged with Tc-99m (V) DMSA obscured the recurrent malignant thymoma. Although Tc-99m (V) DMSA is a useful tumor-seeking agent, Tc-99m MIBI and Tc-99m tetrofosmin SPECT are preferred to Tc-99m (V) DMSA to detect primary and recurrent malignant thymoma.
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