The effect of indomethacin 1% ophthalmic suspension on the pupil during extracapsular cataract surgery
作者:
Per Lykke Gregersen,
Per Julius Nielsen,
Kelvin Kamp Mortensen,
期刊:
Acta Ophthalmologica
(WILEY Available online 1992)
卷期:
Volume 70,
issue 4
页码: 522-524
ISSN:1755-375X
年代: 1992
DOI:10.1111/j.1755-3768.1992.tb02124.x
出版商: Blackwell Publishing Ltd
关键词: extracapsular cataract extraction (ECCE);indomethacin;prostaglandin;surgically induced miosis
数据来源: WILEY
摘要:
AbstractFifty‐six patients who underwent extracapsular cataract surgery were randomized in two groups with 28 patients in each group. Group 1 was treated with standard preoperative dilation regime and group 2 received in addition indomethacin 1% ophthalmic solution. Horizontal and vertical pupil diameter measurements were taken before capsulotomy, before exprimation of the lens nucleus and before lens implantation. The size of the pupil at the time of capsulotomy and at the time just before lens exprimation was greatest in the non‐indomethacin treated group, but at the time of lens implantation the pupil of the indomethacin treated group was greatest. It is concluded that even though indomethacin seems to be able to inhibit surgically induced miosis, probably through its inhibitory effect on prostaglandine synthesis, the effect is only marginal and from a clinical point of view it cannot be recommen
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