SummaryStarting from two cases of intestinal involvement in von Recklinghausen’s neurofibromatosis, one associated with obstructive jaundice and the other complicated by sarcomatosis transformation and bleeding, the authors report the frequency and the clinical features of digestive localizations. In a third case of neurofibromatosis, endocrine tumors were observed; this association is also discussed.In a series of 20 patients with neurofibromatosis 30 % presented visceral and 15 % digestive involvement. Among 4 cases of bleeding, two were due to digestive localization of the disease.