A 39,X/40,XY/41,XYY mosaic male mouse
作者:
RK. Das,
AK. Behera,
期刊:
Cytogenetic and Genome Research
(Karger Available online 1984)
卷期:
Volume 38,
issue 2
页码: 138-141
ISSN:1424-8581
年代: 1984
DOI:10.1159/000132046
出版商: S. Karger AG
数据来源: Karger
摘要:
Cytogenetic analyses of bone marrow and gonadal cells in a male mouse, which appeared to be normal, revealed mosaicism in both tissues. Three chromosome complements, 39, X, 40, XY, and 41, XYY, were found in both bone marrow and spermatogonia, while only the last two complements were found in spermatocytes. In this mouse, unlike in the human, the XYY cells showed a proliferative advantage over the XY cells. In XYY cells at diakinesis/metaphase I the gonosomes showed all possible types of association, and a pairing advantage of the X chromosome was clearly demonstrated. The fertility of the mouse was not determined. However, since the epididymal sperm count was reduced by only 55% and the incidence of sperm head abnormality was near normal, it is not evident that the mouse was sterile.
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