Sickle cell anemia and trait in a population of southern india
作者:
Gary Brittenham,
B. Lozoff,
J. W. Harris,
V. S. Sharma,
S. Narasimhan,
期刊:
American Journal of Hematology
(WILEY Available online 1977)
卷期:
Volume 2,
issue 1
页码: 25-32
ISSN:0361-8609
年代: 1977
DOI:10.1002/ajh.2830020104
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: sickle hemoglobinopathy;population survey;India;malaria
数据来源: WILEY
摘要:
AbstractIn an ethnic group in southern India, the Irula, seven individuals with sickle cell anemia were found to manifest only mild illness. Although a relatively high level of fetal hemoglobin was present in one, none of the factors thought to ameliorate the course of sickling disorders could be identified in the remaining six. In a random population survey, sickle hemoglobin was found in 90 of 292 Irula (31%). In those with sickle cell trait, the proportion of sickle hemoglobin in hemolysates (mean = 26%, range 19–32%) was substantially lower than that reported for any other populatio
点击下载:
PDF
(499KB)
返 回