Immunohistological Study of Captopril-Induced Late Cutaneous Eruptions
作者:
N. Bretin,
B. Dreno,
B. Bureau,
P. Litoux,
期刊:
Dermatology
(Karger Available online 1988)
卷期:
Volume 177,
issue 1
页码: 11-15
ISSN:1018-8665
年代: 1988
DOI:10.1159/000248493
出版商: S. Karger AG
关键词: Captopril;Immunolabeling;Skin;Pemphigus;Lichenoid eruption
数据来源: Karger
摘要:
Immunohistological study of dermal infiltrate from two pempigus- and one captopril-induced lichenoid eruption showed the presence of a CD8 (T suppressor) infiltrate that resembled that found in skin eruptions induced by graft-versus-host disease. It is suggested that a T cell cytotoxic reaction occurs in the epidermis that might be triggered by captopril-induced modification of keratinocytic antigens
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