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Analysis of Urinary Calculi Containing Triamterene. Presence of A Glucuronic Metabolite.

 

作者: J.F. Sabot,   Ph. Bernard,   H. Pinatel,   M. Boucherat,  

 

期刊: Analytical Letters  （Taylor Available online 1996）
卷期: Volume 29, issue 8  

页码: 1319-1327

 

ISSN:0003-2719

 

年代: 1996

 

DOI:10.1080/00032719608001484

 

出版商: Taylor & Francis Group

 

关键词: Calculus;Triamterene;Infrared Spectroscopy;Mass Spectroscopy;Metabolites;Glucuronic Acid

 

数据来源: Taylor

 

摘要:

Urinary calculi containing triamterene were described since 1979. We have studied calculi, obtained from an anuric patient, by surgery. This paper describes the advanced techniques that were used, such as infrared spectroscopy, nuclear magnetic resonance, mass spectrometry associated with thin-layer chromatography or gas chromatography, to show the presence of unusual compounds. Six metabolites are found, among them pure triamterene (96%), hydroxy-triamterene, and a particular metabolite containing glucuronic acid.

 

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