Surgical Repair of Bone Defects of the Ear Canal Wall with Flexible Hydroxylapatite Sheets: A Pilot Study
作者:
Diego Zanetti,
Nader Nassif,
Antonino Antonelli,
期刊:
Otology & Neurotology
(OVID Available online 2001)
卷期:
Volume 22,
issue 6
页码: 745-753
ISSN:1531-7129
年代: 2001
出版商: OVID
关键词: Outer ear canal wall reconstruction;Flexible hydroxylapatite;Chronic otitis media;Cholesteatoma
数据来源: OVID
摘要:
ObjectiveEvaluation of suitability of flexible composite sheets (hydroxylapatite and polymer) for outer ear canal (OEC) wall reconstruction in tympanoplasty.Study DesignProspective, open label pilot study.SettingUniversity and regional hospital.PatientsForty-two randomly selected patients with chronic otitis media (n = 20) and cholesteatoma (n = 22) among 356 patients admitted between 1996 and 1997.InterventionsEradication of disease through a partial or total canal wall down mastoidectomy; immediate reconstruction of canal wall with flexible composite sheet (hydroxylapatite and polymer) and connective tissue graft.Outcome MeasuresAnatomic integrity of the OEC and neotympanum, extrusion rate, complications.ResultsAt minimum follow-up of 24 months: recurrent cholesteatoma (n = 0), residual cholesteatoma (n = 3/22) (13.6%) in the mesotympanum (none behind the hydroxylapatite sheet or in the attic or antrum). The neotympanum was intact in 38 ears (90.4%), reperforated in 2, and severely retracted and lateralized in 1, respectively. Anatomic integrity of the OEC was obtained in 37 (88%) of 42 patients; stenosis or membranous synechiae were observed in 5 ears and treated in the office. Extrusion of the hydroxylapatite sheet occurred in 7 patients (16.6%) because of purulent otorrhea and granulation tissue formation. Surgical revision achieved complete epithelialization of the rebuilt canal wall in 33 ears (78.6%).ConclusionsA dry, disease-free ear and normal anatomy may be expected 2 years postoperatively in more than three-fourths of the patients treated using the described surgical technique. Complete protection with a connective tissue graft is essential to avoid extrusion of the implant. The failure rate is significantly higher if otorrhea is present at the time of the operation.
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