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The Effect of Vasoactive Agents on the Contractions of the Initial Lymphatics of the Bat’s Wing

 

作者: Joseph L. Unthank,   Robert D. Hogan,  

 

期刊: Journal of Vascular Research  (Karger Available online 1987)
卷期: Volume 24, issue 1-2  

页码: 31-44

 

ISSN:1018-1172

 

年代: 1987

 

DOI:10.1159/000158669

 

出版商: S. Karger AG

 

关键词: Bat’s wing;Initial lymphatics;Spontaneous contractions;Inflammatory mediators;Neurotransmitters;Vasoactive substances;Lymph formation

 

数据来源: Karger

 

摘要:

The effect of vasoactive agents on the spontaneous contractions of the initial lymphatics of the bat’s wing was investigated. Initial lymphatic contractile frequency and pulsatile pressure were measured with the servo-null micropressure system. Norepinephrine, phenylepinephrine, isoproterenol, acetylcholine, histamine, serotonin, bradykinin, prostaglandin F2a, prostaglandin E2, indomethacin and ibuprofen were delivered to the immediate vicinity of the initial lymphatic by microinjection or iontophoresis. Only bradykinin produced changes in initial lymphatic contractions which were significantly different from control. The response to bradykinin was characterized by an increase in the frequency, strength or duration of the contractio

 

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