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Dietary Vitamins A, C, and E and Selenium as Risk Factors for Cervical Cancer

 

作者: Martha Slattery,   Thomas Abbott,   James Overall,   Linda Robison,   Thomas French,   Christopher Jolles,   John Gardner,   Dee West,  

 

期刊: Epidemiology  (OVID Available online 1990)
卷期: Volume 1, issue 1  

页码: 8-15

 

ISSN:1044-3983

 

年代: 1990

 

出版商: OVID

 

关键词: beta-carotene;case-control;cervical neoplasms;cigarette smoking;selenium;vitamin A;vitamin C;vitamin E

 

数据来源: OVID

 

摘要:

The relation between cervical cancer and dietary intake of vitamins A, C, and E, beta-carotene, and selenium was examined in a population-based case-control study in Utah. Cervical cancer cases (n = 266) and population-based controls (n = 408) were interviewed between 1984 and 1987. Protective effects were observed for vitamins A, C, and E and beta-carotene but were attenuated by age, level of education, and lifetime cigarette use. Associated risk (comparing highest with lowest quartiles of intake) went from 0.53 (crude) to 0.71 (adjusted) for vitamin A; from 0.55 (crude) to 0.82 (adjusted) for beta-carotene; from 0.45 (crude) to 0.55 (adjusted) for vitamin C; from 0.58 (crude) to 0.60 (adjusted) for vitamin E; and from 0.95 (crude) to 0.70 (adjusted) for selenium. Adjustment for number of sex partners and church attendance, factors significantly related to cervical cancer risk, only slightly attenuated these adjusted risk estimates.

 

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