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CRYSTALLIZATION KINETICS AND PRODUCT PURITY OF α-GLUTAMIC ACID CRYSTAL

 

作者: CLIFFORDY. TAI,   WEI-LI SHEI,  

 

期刊: Chemical Engineering Communications  (Taylor Available online 1993)
卷期: Volume 120, issue 1  

页码: 139-152

 

ISSN:0098-6445

 

年代: 1993

 

DOI:10.1080/00986449308936130

 

出版商: Taylor & Francis Group

 

关键词: Glutamic acid;Crystallization kinetics;Product purity;MSMPR crystallizer

 

数据来源: Taylor

 

摘要:

A continuous mixed-suspension mixed-product removal lpar;CMSMPR) crystallizer was used to study the crystallization kinetics and product purity of glutamic acid crystal in pure solution and impure solution with L-phenylanaline as the impurity. Under the assumption that the crystal growth rate was a function of crystal size, the population balance equation was solved to give the crystal growth and nucleation rates by use of the steady-state population density data. The crystal growth and nucleation rates were suppressed by the presence of impurity. The impurity contents in the crystal products, which were analyzed by a HPLC pre-column method, were found to be related to crystal size, supersaturation, and impurity concentration of solution

 

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