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Effect Of Dipyridamole On Blood Platelets In Pharmacological Experiments

 

作者: HaarmanW.,   KadatzR.,  

 

期刊: Acta Clinica Belgica  (Taylor Available online 1975)
卷期: Volume 30, issue 3  

页码: 190-194

 

ISSN:1784-3286

 

年代: 1975

 

DOI:10.1080/17843286.1975.11716996

 

出版商: Taylor&Francis

 

关键词: Dipyridamole;Platelet aggregation;Laboratory methods in vitro;Laboratory methods in vivo.

 

数据来源: Taylor

 

摘要:

SummaryIn this paper the antiplatelet and antithrombotic activity of Dipyridamole is described. In in vitro tests the effect on platelet adhesion was found to be more pronounced than that on different types of aggregation.In in vivo models a good and long lasting inhibiting effect on primary haemostasis was seen in mice. An antithrombotic effect was achieved in a thrombus formation test in rats. The dose of Dipyridamole used in these in vivo experiments was only 10mg/kg orally.

 

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