Effect Of Dipyridamole On Blood Platelets In Pharmacological Experiments
作者:
HaarmanW.,
KadatzR.,
期刊:
Acta Clinica Belgica
(Taylor Available online 1975)
卷期:
Volume 30,
issue 3
页码: 190-194
ISSN:1784-3286
年代: 1975
DOI:10.1080/17843286.1975.11716996
出版商: Taylor&Francis
关键词: Dipyridamole;Platelet aggregation;Laboratory methods in vitro;Laboratory methods in vivo.
数据来源: Taylor
摘要:
SummaryIn this paper the antiplatelet and antithrombotic activity of Dipyridamole is described. In in vitro tests the effect on platelet adhesion was found to be more pronounced than that on different types of aggregation.In in vivo models a good and long lasting inhibiting effect on primary haemostasis was seen in mice. An antithrombotic effect was achieved in a thrombus formation test in rats. The dose of Dipyridamole used in these in vivo experiments was only 10mg/kg orally.
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