AbstractPerformance in science reasoning tasks is a significant objective in modem science instruction and increasing emphasis is being placed on the development of higher cognitive processes in science education. An empirical analysis of the relationship between science reasoning skills and the amount of information acquired during science learning as predicted by a neuromathematical model of information processing is presented. As the neuromathematical model includes a variable representing verbal ability, it is to be expected that a direct relationship exists between the amount of knowledge gained as predicted by the model and reasoning ability. The purpose of this research is to derive a formal quantitative statement for the relationship between knowledge acquisition predicted by the neuromathematical equation and scientific reasoning skills. A linear regression equation is obtained relating performance on a science reasoning task to the amount of information acquired as predicted by the neuromathematical model. This research provides a first approximation to providing a theoretical and empirical link between information processing and higher cognitive thought processes in science education.