Interference of maternal antibodies with the immune response of foals after vaccination against equine influenza
作者:
C. van Maanen,
G. Bruin,
E. de Boer‐Luijtze,
G. Smolders,
G. F. de Boer,
期刊:
Veterinary Quarterly
(Taylor Available online 1992)
卷期:
Volume 14,
issue 1
页码: 13-17
ISSN:0165-2176
年代: 1992
DOI:10.1080/01652176.1992.9694319
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
The purpose of the study was twofold First, using two groups of 22 foals each, we investigated the extent to which maternal antibodies interfere with the humoral response against equine influenza. The foals were born to mares that had been vaccinated twice yearly against influenza since 1982. Foals of group I were vaccinated three times at early ages (12 16, and 32 weeks of age), and foals of group II were likewise vaccinated but at later ages (24, 28, and 44 weeks of age). After the first and second vaccinations, neither group showed an increase in antibodies that inhibit haemagglutination. Group II foals, however, had a significantly stronger antibody response against nucleoprotein after the second vaccination than the foals of group I. After the third vaccination, group II foals had a significantly stronger and longer lasting antibody response against haemagglutinin than the foals of group I. However, the antibody response to nucleoprotein was comparable in both groups.
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